| 49 | | - yes and no: No, for the short reads where the position on a reference seq is known you could just store the position rather than the entire read. Yes, imagine a user find a new unknown SNP at a given position: he will want to get the sequences/quality(?) of all the reads overlapping a the mutation for this assembly as well as for the other individuals' genome. - Pierre |
| | 49 | - yes and no: No, for the short reads where the position on a reference seq is known you could just store the position rather than the entire read. Yes, imagine a user find a new unknown SNP at a given position: he will want to get the sequences/quality(?) of all the reads overlapping a the mutation for this assembly as well as for the other individuals' genome. - Pierre |
| | 50 | - this is only true for genome resquencing. for RNA->genome mapping data you do want the read since it can capture RNA modifcations which are not the same as a SNP -- jessica |
