Changes between Version 4 and Version 5 of SatelliteTranscriptionRegulation

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Timestamp:
2009/03/17 16:48:25 (15 years ago)
Author:
yjkim8
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  • SatelliteTranscriptionRegulation

    v4 v5  
    3434 
    3535== TODOs == 
     36Transcriptional regulation 
     37Genomic variation(SNP, CNV….) using NGS 
     38Data, sequence 
     39Variation detection, 
     40Annotation 
     41 
     42Dr. Liu    , 
     43 
     44Purpose: Make a unified solution tool that biologists want in their functional, molecular studies. -Identify feasible techniques and economic solutions for them. 
     45 
     46The questions that should be addressed. 
     471.      Transcription binding sites, modulations 
     482.      Histon binding sites 
     493.      Histon modification 
     504.      SNPs, SNP chips 
     515.      Expression (mRNA or cDNA chips) 
     526.      miRNA or RNAi 
     537.      methylation (epigenetics) 
     548.      CNV (copy number variation) 
     559.      Protein structure 
     5610.     Protein chips 
     5711.     Tissue arrays 
     5812.     Cell-level functional studies 
     5913.     Pathway analysis 
     6014.     Next generation sequencing 
     6115.     OMIM or disease DB 
     6216.     Comparative genomics 
     6317.     Technologies unknown yet 
     64 
     65How: Define each question in terms of biologists’ interests. Describe the limits of each question. Find the best or second best tools for each question.  How to combine the questions for the sake of biologists (input and output data) 
     66 
     67Find out the best example of these kind of approaches (ex. SRS of Lions, ) 
    3668 
    3769 * check [http://sysbio.kribb.re.kr:8080/fesd/ FESD II] schema